We use Fully Enzymatic Synthesis (FES)™ technology to accelerate
the production of long, pure, and accurate DNA,
regardless of complexity.
Synthetic DNA is the life force driving discoveries in clinical medicine, pharmaceuticals, agriculture, and food. But the chemical synthesis process we’ve come to rely on only produces short DNA oligos. That’s why we started an enzyme-based DNA synthesis revolution, so you don’t have to choose between fast turnarounds, oligo length, and purity.
Therapeutics/Vaccines
Immunotherapy
Agriculture
Nanotechnology
Molecular Assemblies’ Fully Enzymatic Synthesis technology operates at 99.9% step-wise incorporation efficiency delivering highly accurate oligonucleotides without the need for timely and expensive PAGE or HPLC purification. After nearly 50 years of development and optimization, chemical synthesis has plateaued at 99.6% step-wise incorporation efficiency, providing low purity of final product and limiting total length.
High or Low GC Content
Long Homopolymer Stretches
Repetitive Elements
Molecular Assemblies’ Fully Enzymatic Synthesis has been optimized to operate up to 70C which melts most secondary structure and allows our process to synthesize even traditionally “difficult” sequences easily. In addition to higher temperature, the process also takes place at a neutral pH environment which is both good for the DNA and the environment unlike the harsh acids and bases used in chemical synthesis degrade the final product, causing truncated species, and are difficult to dispose of.
Molecular Assemblies’ Fully Enzymatic Synthesis synthesizes long oligos quickly, requiring no post-synthesis purification processes to get highly pure product. Our modular manufacturing platform is able to kick off frequently as orders come in, enabling fast order to shipment turn-around time with highly predictable first-time pass rates.
Long
With our proprietary enzymatic synthesis technology, we can produce DNA up to 400 bases with ease.
Pure
An in-process purification step yields clean DNA without the need for lengthy and expensive post-synthesis purification.
Accelerated
The ability to produce long oligos directly without added purification steps means that we can deliver long, pure DNA faster.
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